![]() From top to bottom panel the visually apparent magnitudes of CAP and ANN increase resulting in a higher scores noted on the left of the panels. ECochG recordings with increasing evidence of neural activity in the form of CAP and ANN. The red circles in the spectrum indicate the level required for the peaks to be significant (see Methods). Blue portion within the blue background indicates the ongoing, or steady-state portion of the ECochG response containing the CM and ANN. Red portion of the waveform at the onset of the response indicates a CAP. ECochG response and to 500 Hz and the corresponding FFT spectrum. All rights reserved.ĮCochG waveform and energy spectra characteristics of CI subjects. In both subject populations, weaker evidence of neural activity was related to failure to achieve open-set speech perception.Īuditory nerve neurophonic Auditory neuropathy spectrum disorder Cochlear implants Compound action potential Electrocochleography.Ĭopyright © 2017 Elsevier B.V. There was also strong correlation between PTA and speech perception outcome in ANSD group. In both subject groups, the TRs correlated with outcomes but these measures were notably larger in the ANSD group. In both populations, nerve score was sensitive in identifying subjects at risk for not acquiring open-set speech perception, while the CAP and the ANN were more specific. In the ANSD group, the PTA accounted for 69.3% of the variability, but there was no relationship with outcomes in the non-ANSD group. Most ANSD (73.3%) and non-ANSD (87.8%) subjects achieved open-set speech perception TR accounted for 33% and 20% of variability in the outcomes, respectively. On average, TR was larger in ANSD than in non-ANSD subjects. Standard statistical methods were applied. ![]() Performance on open-set monosyllabic word tests was the outcome measure. The compound action potential (CAP) and the auditory nerve neurophonic (ANN) in ECochG waveforms were used to estimate nerve activity and calculate nerve score. The total response (TR) is the sum of spectral peaks of responses across frequencies. To assess electrocochleography (ECochG) to tones as an instrument to account for CI speech perception outcomes in children with auditory neuropathy spectrum disorder (ANSD).Ĭhildren (<18 years) receiving CIs for ANSD (n = 30) and non-ANSD (n = 74) etiologies of hearing loss were evaluated with ECochG using tone bursts (0.25-4 kHz).
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